Tetramethylpyrazine attenuates PPAR-γ antagonist-deteriorated oxazolone-induced colitis in mice
نویسندگان
چکیده
منابع مشابه
Tetramethylpyrazine improves oxazolone-induced colitis by inhibiting the NF-κB pathway.
PURPOSE Tetramethylpyrazine (TMP) is an effective Chinese plant-derived medicine for colitis in the clinic, but the underlying molecular mechanisms of its use remain poorly understood. The purpose of this study was to investigate the mechanisms involved in its therapeutic action. METHODS A colitis mouse model was induced by oxazolone enema. TMP was administered at 80 mg/kg/day and sulphasalaz...
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ژورنال
عنوان ژورنال: Molecular Medicine Reports
سال: 2011
ISSN: 1791-2997,1791-3004
DOI: 10.3892/mmr.2011.721